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Monday, March 12, 2012

An Invitation: Off Topic From Life Extension

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Shadow Leaders (puppeteers) and Alternative Governments (secret controllers) are notions which have now gone beyond the realm of futuristic sci-fi books and movies, 'crackpot' websites, and other forms of either imagination-fueled or paranoia-fueled media and become increasingly prevalent in the headlines and subject matter of articles and posts in highly-respected media and blogs.

Such authors as Dan Brown, Vince Flynn, Robert Ludlum, David Icke, and such mainstream television shows as The Unit, StrikeBack, Burn Notice are pressing the notion of secret societies, black-ops government units, private armies, cabals, conspiracies, privileged families pulling strings, and very small, secretive, amoral groups exerting incredible force (without allegiance to any country or cause) over the population and resources of the entire planet.

The Warren Commission, Area 51, Roswell, Fort Knox, Ruby Ridge, BP's ecological accident, Stealth Weapons, The World Trade Center Tragedy, the financial meltdown of the World Banking System, leaked correspondence from some very large and influential companies -- all of these magnetically, hypnotically pull our minds into at least contemplating the frightening and almost incomprehensible possibility of massive cover-ups, stratospheric power plays, para-governmental contractors in pivotal positions, and an elaborately-woven quilt of lies compounded upon lies.

You cannot help but think about the possibilities. Unthinkable Possibilities....yet we think about them.

Let's examine them together in A New Twitter Group. There is a great deal of fiction and fantasy out there, but what about the part that might actually be true? The best lies are concealed in half-truths, and dangerous truths are strategically debunked by tossing them in with the ravings of 'lunatics,' 'paranoids,' and 'extremists.' Join us.

Details follow, and all inquisitive minds are welcome - once there, you can draw your own conclusions. We don't pass judgment on our members -- we pass information and intelligence on to them for them to evaluate.

Again, join us.

Douglas E Castle







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Thursday, January 12, 2012

Anti-Aging, Increased IQ, Renewed Strength and Endurance.

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Great news for you fans of anti-aging, longevity, cognitive enhancement, improved physical performance and eternal youth! Commencing on January 15, 2012 (Happy New Year, in case I'd forgotten), this blog will be actively posting with cutting-edge news about what you can do to live a longer, happier, healthier life, as well as collection of resources and sources for you to get just what you need in order to accomplish these things.

This blog, LIFE EXTENSION AND ENHANCEMENT..., is the companion blog to BRAINTENANCE, a fast-growing favorite amongst the intellectual elite. Please join us there, too.

I look forward to seeing you very soon.

Douglas E Castle [http://aboutDouglasCastle.blogspot.com]




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Wednesday, August 10, 2011

Dopamine Versus Norepinephrine: Macuna Pruriens Versus Amphetamine-Like Supplements

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Dopamine and Norepinephrine (Noradrenalin) are neurotransmitters which act on the body's physiology and the mind's emotional state (both are physiologically active and psychoactive as well), they act by very different mechanisms. Both have a psychotonic and stimulant effect, but each has its own place within the hierarchy of better living through careful, well-moderated supplementation.

Being simplistic, norepinephrine creates a state of hypervigilance, "flight or fight" responses, increased physical strength, decreased physical sensitivity, secretion of cortisol, pulse rate and blood pressure elevation, and, in many cases, anxiety. The use of precursors to release this neurotransmitter (such as phenylethylamine, pseudoephedrine, methamphetamine, adderall and a host of others) tend to vary in intensity, half-life and side effects. They do not generally serve well as antidepressents, they produce a level of anxiety and hyperstimulation, and when their effects have worn off, the body feels ravaged and the mind goes through a depressed recovery cycle. They are all appetite suppressants, and are used by fitness buffs and bodybuilders, as well as soldiers in the field of combat. They are crude CNS stimulants. They do not increase pleasure (generally), but they can create wakefulness, focus (in some), and greater endurance for physical challenges.

Norepinephrine acts as a potent appetite suppressant, whereas dopamine is neither as immediately effective or as powerful an appetite suppressant even as it accumulates in the body, although it does have some effect in this regard.

In contrast, dopamine precursors and proto-supplements tend to take longer to have a discernible effect, and they work directly on the mind's pleasure and wakefulness centers. Some of these precursors are macuna pruriens (extracted from the velvet bean and containing approximately 15% levodopa (L-Dopa), and Sinemet, which is a brand name for carbidopa, a drug that is used (in conjunction with deprenyl) to treat Parkinson's disease, and proactively for treatment of senile dementia. Dopamine is associated with increased aggressiveness, sex drive, and antidepressant qualities in certain individuals. Dopaminergic supplements are not as hyper-stimulating to the CNS, and are less prone to cause precipitous anxiety or violent behavior. Of course, as sufficient dopamine builds up in certain parts of the brain, its potential to be dangerously disruptive increases.

Another advantage of dopaminergic agents is that they do help in certain cases of narcolepsy, unipolar depression, and in offsetting some of the anti-libidinous effects of SSRIs and SNRIs taken by disthymic, depressed or demotivated individuals. SNRIs are interactive in stimulating norepinephrine production and longevity in the synapse -- these often cause anxiety in patients being treated for depression.

If you must experiment, be certain that your cardiovascular and psychiatric health can tolerate small doses of these substances, and take them only under a health professional's supervision.

My personal inclination would be to use the minimal effective dose of PEA prior to intensive, physically demanding activity or a scheduled workout, but to take small periodic doses of dopaminergic supplements and carefully monitor your mood and decision making capabilities. As a psychotropic supplement for cognitive enhancement, focus and additional wakefulness, dopamine has far more of what you seek than any of the norepinephrine enhancers. 

Douglas E Castle (http://aboutDouglasCastle.blogspot.com)

Other Blogs:
http://LifeExtensionAndQuality.blogspot.com
http://Links4LifeAlerts.com
http://SendingSignals.blogspot.com
http://www.TNNWC.com





You may wish to Google "Erowid" to find out more about macuna pruriens, phenylethylamine, and a long list of psychotropic, cognitive-enhancement and mind-altering drugs. Much of the information is anecdotal, and many of the substances described are either available only by prescription, or are controlled or illegal. Be careful. Keep it academic.




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ARTICLE ARCHIVE



RESOURCE AND RESEARCH SECTION




NOOTROPICS, ENTHEOGENS AND COGNITIVE ENHANCEMENT

Following is a list of links to information and sites about various nootropics, entheogens and "smart drugs" for your ready reference. Be advised that the author does not express any opinion whatsoever regarding the safety, availability, legality, effectiveness or any other aspect of any product, formulation or preparation discussed.

The author does not offer health, medical or legal advice, and does not endorse the accuracy, completeness or utility of any of the informational items below:



ANTI-AGING AND LONGEVITY




PERFORMANCE ENHANCEMENT - PHYSICAL AND ATHLETIC




INCREASED ENERGY, FOCUS AND AWARENESS - PHYSICAL AND MENTAL




ALTERED PERCEPTION, EXPLORATION AND EXPERIMENTATION




TRANSHUMANISM




PHYSICAL FITNESS, STRENGTH, FLEXIBILITY, COORDINATION AND ENHANCED HEALTH




OTHER RELATED TOPICS OF INTEREST